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  • benoit busser

Just Released ! read our review "LIBS Imaging for Material and Biomedical Applications"

I am happy to announce that our review entitled "Laser-Induced Breakdown Spectroscopy Imaging for Material and Biomedical Applications Recent Advances and Future Perspectives" is out, just published in Analytical Chemistry.


This is an “invited review” for the annual special Issue “Fundamental and Applied Reviews in Analytical Chemistry 2023”



Details about the article:


Laser-Induced Breakdown Spectroscopy Imaging for Material and Biomedical Applications Recent Advances and Future Perspectives.


Vincent Gardette (a), Vincent Motto-Ros (a), César Alvarez Llamas (a), Lucie Sancey (b),

Ludovic Duponchel (c), and Benoit Busser (b),(d),(e)*


Affiliations

a) Université de Lyon, Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, Villeurbanne, France

b) Univ. Grenoble Alpes, Institute for Advanced Biosciences, Inserm U 1209 / CNRS 5309, 38000 Grenoble, France

c) Univ. Lille, CNRS, UMR 8516 – LASIRE – Laboratoire de Spectroscopie pour Les Interactions, La Réactivité et L’Environnement, Lille, F-59000, France.

d) Department of laboratory medicine, Grenoble Alpes University Hospital, 38000, Grenoble, France

e) Institut Universitaire de France, France


*Email: bbusser@chu-grenoble.fr



Analytical Chemistry 2023; 95 (1) 49-69

DOI : https://doi.org/10.1021/acs.analchem.2c04910


Abstract

Laser-induced breakdown spectroscopy (LIBS) is a versatile analytical tool for studying the elemental composition of any kind of sample, such as solids, liquids or gases. One of the latest developments in this technique is the ability to use it for elemental imaging, that is to say spatially resolved surface analysis. LIBS imaging is becoming a very attractive and popular technique for the qualitative and/or quantitative spectrochemical characterization of specimens for a wide range of applications. Because of its unique set of intrinsic advantages, LIBS imaging is frequently preferred over competitive and complementary techniques for elemental imaging.

This review recapitulates the technical fundamentals of LIBS imaging and focuses on significant applications that have received the most promising attention and have undergone major advances during the last three years in the industrial, geological and biomedical fields. We also discuss the current limitations that hinder the further development of LIBS imaging, as well as perspectives on the use of LIBS as a part of multimodal imaging strategies, the contribution of chemometrics, and ideas for improving the limits of detection and quantification aspects.

Keywords: LIBS imaging, geology, industry, biomedicine, chemometrics

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